Here is one of the first large-scale scientific projects based on HyperCard: a multi-stack manual on North American Trilobites made by Dr Robert E. Sloan, professor of paleontology at the University of Minnesota. Trilobites are a class of extincted marine Arthropods of the Paleozoic Era.
https://en.wikipedia.org/wiki/Trilobite
The stack uploaded on this page covers anatomy, classification, paleoecology, and evolutionary history of Trilobites of the Ordovician period, about 450 million years ago. More details about this project on the preface card ("Stack Info" button).
Minimum requirements:
Any computer system able to run HyperCard 1.x or later.
Tested successfully on:
Basilisk II for MacOSX w/System 7.5.5 & HyperCard Player 2.1
SheepShaver for MacOSX w/MacOS 9.0.4 & HyperCard 2.4.1